Saad Sarwana tries to juggle careers in physics and comedy, and Jean Zarate is torn between science and music until a tragic event brings both into perspective.

Astrophysicist Jesse Shanahan tries to uncover the mysteries behind both black holes and her own chronic pain, and comedian Sarah Pearl checks into a psychiatric hospital after having suicidal thoughts.

Rattled by a recent heartbreak, neuroscientist Prabarna Ganguly makes a mistake in the lab, and marine ecologist Kirsten Grorud-Colvert has an unexpected encounter with a hammerhead shark. 

Biochemist Melanie McConnell encounters unexpected resistance when she tests an experimental cancer treatment, and rape survivor Mo Culberson helps train doctors to treat other rape survivors.