Comedian Riley Silverman attempts to use science to change the course of puberty and comedian Ang Buxton explores the differences in gender expectations from the football field to the middle school cafeteria.

Diabetes runs in Michele Carlo’s family and she’s determined not wind up like them and comedian Gastor Almonte comes to terms with his new diabetes diagnosis.

Math teacher Theodore Chao goes all out for Pi Day at his school and Debbie Char learns what a flash point is while cooking a meal for her date.