When the local science museum looks to hire performers, David Nett believes he's the perfect man for the job, and after finding out her uterus never developed, scientist Chivonne Battle searches for an alternative way to become a mother.

Comedian Zack Stovall reevaluates his past battles with his mother in light of a new diagnosis, and Audrey Kearns' big opportunity to appear as a panelist at a "nerd-convention" turns disastrous when she has an unexpected reaction to a new antidepressant.

After passing out on the NYC subway, comedian Mike Brown is forced to take a deeper look at his mental health, and Emily Yarrison survives her suicide attempt and has to ask herself a whole new set of questions.

Heather Williams trades in her physicist labcoat for motherhood, and wonders if she can return, and Mary Garcia-Cazarin discovers she's pregnant just as she is offered a prestigious science policy fellowship, and worries about whether she can't cope with both.

A parent-teacher conference leads Eugenia Duodu to question whether she can be a scientist, and At 13 years old Misha Gajewski has to undergo a jaw surgery to fix a face she is just getting used to.