After surviving breast cancer, comedian Ophira Eisenberg hates the pink breast cancer awareness ribbon, and after the sudden death of his mom, Richard Kemeny feels numb to the world and his feelings.

Devon Kodzis thought they had their anxiety under control until a routine doctor appointment, and naturally anxious neuroscientist Tammy Spence becomes preoccupied with her dog’s health.

One moment Keith Mellnick is cycling home, the next he’s in the emergency room of the hospital with no idea what happened to him, and medical student Fabiola Plaza feels compelled to help a woman on the New York subway get a doctor’s appointment.

After a neurological disorder leaves Tracey Starin visually impaired, she struggles to fill the void of her love for reading, and at first comedian Ayanna Dookie doesn’t take her Lupus diagnosis seriously.