Keoni Mahelona leaves his home in Hawaii in pursuit of science, and after growing up wealthy, Chuck Collins's thinking is transformed by his work with mobile home park tenants.

Jean Ansolabehere is surprised to find herself falling in love with a woman in her lab, and as a child, psychologist Scott Barry Kaufman is told that he's doomed by a low IQ score.

Anthropologist Andrew Oberle barely survives an attack by the chimpanzees he was studying, and science becomes a solace for cosmologist Renee Hlozek after her father dies suddenly.

A sudden illness threatens to derail Maia Pujara's neuroscience PhD, and after growing up in humble circumstances in St. Lucia, biologist Whitney Henry feels like an imposter at Harvard.

Actor Gail Thomas is invited to take part in a study testing mushrooms as treatment for depression in cancer survivors, and comedian Myq Kaplan experiments with ayahuasca.